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Among the last men on Earth are Brian (Chris Pine), a rowdy brawler, and his brother Danny (Lou Tayler Pucci), a sensitive Ivy Leaguer, who are traveling across the southwestern United States with gal pals Bobby (Piper Perabo) and Kate (Emily VanCamp). Their destination is California, specifically a remote seaside resort where the brothers spent time as kids. While Brian assumes he's immune -- he spent time waist-deep in corpses and emerged healthy -- the others are not so confident. They wear rubber gloves and face masks and douse everything they touch with disinfectant.
All goes well until the foursome meets Frank (Christopher Meloni) and his very ill daughter (Kiernan Shipka). Frank is searching for a government outpost where scientists claim to have developed a vaccine, and Brian reluctantly agrees to drive them there. Predictably, he's made a bad decision. When the now six encounter a group of Hazmat-suited militants, the situation gets downright gnarly.
While the Pastor brothers weave in a sibling rivalry sub-plot, the bulk of Carriers revolves around the fight for survival. These guys need gas. They need meds. They need food. It is, in many ways, akin to Cormac McCarthy's The Road with lesser stars. From a technical standpoint, the movie is beautifully shot by Director of Photography Benoit Debie (of Irreversible and Calvaire fame), and the directing brothers make excellent use of their New Mexico locales. Although Pine doesn't display the charm that makes him so memorable in Star Trek, the cast's performances are by and large serviceable. Original? No. Surprising? Not even. Brooding? Bleak? Even scary? Sure, on all three counts.
