Cinema's most notorious stoners star in their first, most notorious screen roles. Up in Smoke is the world's most revered -- and most idiotic -- drug movie, a road trip in search of the ultimate high, with Johnny Law on our heroes' tail all the way. Meanwhile, it's non-stop sex, drugs, rock & roll, and drugs. Did I mention drugs? Cheech Marin and Tommy Chong managed to milk this shtick for eight years before they sobered up... with varying degrees of success.

Aka Cheech and Chong's Up in Smoke.